Faculty Information - KOBAYASHI Kenichi |

KOBAYASHI Kenichi

Department / Course

Notre Dame Seishin University Faculty of Human Life Sciences Department of Foods and Human Nutrition

Graduate Scool Graduate Scool of Human Life Sciences Research Course in Comprehensive Human Life Sciences Doctoral Courese

Graduate Scool Graduate Scool of Human Life Sciences Research Course in Food Science and Nutrition Masater's Courese

Graduate Scool Graduate Scool of Human Life Sciences Research Course in Human Living Sciences Masater's Courese

Notre Dame Seishin University Inclusive Education Research Center

Job Professor

Academic conference presentation
2025/08/25	Identification of receptors involved in the process of quinolinic acid-induced renal fibrosis (23rd International Congress of Nutrition　（IUNS-ICN 2025）)
2022/12/24	GAN誘導性NASHモデルマウスでは膵臓のキヌレニン代謝関連遺伝子が軒並み増加する (日本トリプトファン研究会　第41回学術集会)
2022/12/09	Analysis of the effect of coffee polyphenols on the prevention and/or improvement of renal fibrosis (IUNS-ICN 22nd International Congress of Nutrition in Tokyo, Japan)
2022/12/09	Kynurenine metabolism is involved in the link between nonalcoholic fatty liver disease (NASH) and chronic kidney disease (CKD) (IUNS-ICN 22nd International Congress of Nutrition in Tokyo, Japan)
2021/07/04	Identification of the receptors involved in the process of quinolinic acid inducible renal fibrogenesis (75th Annual Meeting of Japan Society of Nutrition and Food Science)
2020/05/16	Searching for brown rice components preventing NAFLD via increasing PGC-1alpha activity
2020/05/16	The Effect of grape polyphenol on renal fibrogenesis in kidney interstitial fibroblasts cells
2020/03/27	Soybean meal prevents high fat diet-induced hepatic steatosis via activation of Peroxisome Proliferator-Activated Receptor γ (PPARγ)/Small heterodimer partner (SHP) pathway in Sprague-Dawley rats
2019/08/21	Antioxidative Activity of three beans ―black soybeans, black matpe and mung beans― (ARAHE The 20th Biennial International Congress 2019)
2018/10/16	Dynamic visualization of anti-colorectal cancer effect of resveratrol using fluorescence labeling strategies (3rd International Conference on Biologically Active Substances, Bioactive Okayama 2018)
2018/10/16	Quinolinic acid phosphoribosyltransferase (QPRT) knockout mouse as a novel noninvasive chronic kidney disease (CKD) animal model and a possible animal model for the search of bioactive compounds with preventive effect in CKD (3rd International Conference on Biologically Active Substances, Bioactive Okayama 2018)
2018/09/19	QUINOLIC ACID, A KYNUREININE PATHWAY METABOLITE, IS THE POSSIBLE TRIGGER MOLECULE OF RENAL FIBROSIS (The 15th International Society for Tryptophan Research (ISTRY) Conference)
2018/05/12	AMPK regulates microtubule formation via MAP1B phosphorylation.
2018/05/12	Brown rice improves the non-alcoholic fatty liver disease via alter the hepatic vitamin A metabolism
2018/05/12	Soybean meal prevents high fat diet-induced hepatic steatosis via activation of Peroxisome Proliferator-Activated Receptor γ (PPARγ)/Small heterodimer partner (SHP) pathway in Sprague-Dawley rats
2017/10/14	Effect of lactic acid bacteria extract fementation products on gut microbiotation rats fed a high fat diet (ISSAAS 2017, International Congress and General Meeting of International Society for Southeast Asian Agricultural Sciences)
2017/10/14	PREGELATINIZED BROWN RICE CAUSES HEPATIC VITAMIN A METABOLIC (ISSAAS 2017, International Congress and General Meeting of International Society for Southeast Asian Agricultural Sciences)
2017/05/21	Renal quinolinic acid accumulation induces noninflammatory renal impairment
2017/05/20	Mechanism analysis of the transient glucose metabolism abnormality in Eker rat(TSC2+/-)
2017/05/20	Pregelatinized brown rice ameliorates steatosis without insulin involvement
2017/05/20	Effects of iron deficiency on intracellular kinetics of CYPs, vitamin D hydroxylase
2016/11/06	EFFECT OF LACTIC ACID BACTERIA EXTRACT FEMENTATION PRODUCTS ON GUT MICROBIOTAIN RATS FED A HIGH FAT DIET (ISSAAS 2016, International Congress and General Meeting of International Society for Southeast Asian Agricultural Sciences)
2016/11/06	PREGELATINIZED BROWN RICE IMPROVE PANCREATIC DISORDER BY DECREASING SERUM INSULIN LEVEL IN OBESE MODEL ZUCKER FATTY RAT (ISSAAS 2016, International Congress and General Meeting of International Society for Southeast Asian Agricultural Sciences)
2016/05/15	Iron deficiency induces cell senescence by increasing oxidative stress
2016/03/30	Dynamic imaging of fluorescently labeled resveratrol in Caco-2 Cells
2016/03/29	Relationship of cell senescence and autophagy in iron deficiency
2015/11/22	Iron deficiency induced autophagy throughactivation of Nrf2/Keap1 system and phosphorylationof p62 (Thr351) against oxidative stress. (6th International Conference on Food Factors (ICoFF2015))
2015/09/19	QPRT KNOCKOUT MICE CAUSES RENAL IMPAIRMENT (The 14th International Society for Tryptophan Research (ISTRY) Conference)
2015/09/10	Calcium signaling induces TSC2 phosphorylation independently of Akt (2015 International Tuberous Sclerosis Complex Research Conference: From Treatment to Prevention)
2015/09/10	Tuberous sclerosis complex 1(TSC1) regulates the Caveolae mediated endocytosis via controlling the Rab5 activity (2015 International Tuberous Sclerosis Complex Research Conference: From Treatment to Prevention)
2015/05/15	Pregelatinized brown rice ameliorates hepatic disorder and pancreatitis in obese model rats (12th Asian Congress of Nutrition (ACN))
2014/12/10	Hepatoprotective effects of pregelatinized rice (White and Brown rice) in obese model rats (East Asia Conference on Standardization of Rice Function (The 3rd International Symposium on Rice and Disease Prevention, Pre-symposium of 9th Asia Pacific Conference on Clinical Nutrition))
2014/12/10	Lipid metabolism improvement effects of pregelatinized rice (white and brown rice) in obese model rats (East Asia Conference on Standardization of Rice Function (The 3rd International Symposium on Rice and Disease Prevention, Pre-symposium of 9th Asia Pacific Conference on Clinical Nutrition))
2014/06/01	The effect of Quinolinic Acid on renal erythropoietin expression
2014/06/01	Lactic acid bacterium fermented soybean product (FiLact) can reduce the serum triglyceride concentration through activating Nrf2 pathway
2014/05/31	The exploratiom of the novel compounds that regulate AMPK
2014/05/31	DNA Microarray Analysis of liver in TSC1^+/-mice.
2014/05/31	A deficiency of Vitamin B12 suppresses the Cholesterol Catabolism through the decreaseding SIRT1 expresssion
2014/05/31	The analysis of GSK3-regulated AMPK activity in the brain
2014/05/30	Analysis of calcium-signaling to mTOR phosphorylation via TSC2.
2014/05/15	Renal accumulation of Quinolinic Acid induces renal fibrosis and decreases erythropoietin expression (14th Asian Pacific Congress of Nephrology （APCN2014）)
2014/05/15	Vitamin B₁₂ deficiency inhibits megalin, cubilin-mediated endocytosis and suppresses reabsorption of vitamin A in the kidney (14th Asian Pacific Congress of Nephrology （APCN2014）)
2014/04/13	Imaging of Fluorescently labeled Olive Polyphenol Hydroxytyrosol in Caco-2 Cells (Focus on Microscopy 2014 (27th International Conference on 3D Image Processing in Microscopy))
2014/04/13	Imaging of the effect of vitamin B12 deficiency on reabsorption of vitamin A in the kidney (Focus on Microscopy 2014 (27th International Conference on 3D Image Processing in Microscopy))
2014/03/28	3-Hydroxytyrosol, but not tyrosol, plays a key role for suppressing osteoclast differentiation
2013/05/26	Bacterial degradation of melanoidin
2013/05/26	Comprehensive analysis of the effects of lactic acid bacteria fermentation soy (FiLact ®) intake on the variation of gene expression in the liver under conditions of high-fat diet
2013/05/26	Effects of an iron-deficient diet on the redox homeostasis of mice various organs
2013/05/25	Mutated TSC modulates the Pentose Phosphate Pathway through activating G6PD
2013/03/26	Research on the melanoidin decolorization by microorganism
2013/03/26	Effects of an iron-deficient diet on the redox homeostasis of mouse heart
2012/12/16	Analysis of SIRT1 activation by ketogenic diet
2012/12/16	The effect of vitamin B-12 on vitamin A transport (The 85th Annual Meeting of the Japanese Biochemical Society)
2012/12/16	Analysis of the mechanism of Rac1 activation through mutant TSC2 (The 85th Annual Meeting of the Japanese Biochemical Society)
2012/12/15	Effect of Vitamin B-12 deficiency on reabsorption of vitamin D and phosphorus in the Kidney
2012/09/17	Separation of microbes to degrade melanoidin formed in cane molasses (11th International Symposium on the Maillard Reaction (ISMR) Nancy)
2012/04/03	Correlative light and electron microscopy studies on human colorectal cancer cells in vitro. (Focus on Microscopy 2012.（25th International Conference on 3D Image Processing in Microscopy, 24th International Conference on Confocal Microscopy）)
2011/03/26	Effect of mutant TSC2 on metabolism via NADPH
2011/03/26	Rac1 activity through TSC2 mutant
2009/10/24	AICAR inhibits apoptosis via AMPK/TSC2/mTOR pathway in Cos-1 cells.
2009/10/24	Caveolin-1 directly interacts with TSC1.
2009/10/24	CaM-dependent alteration of intracellular localizationof tumor suppressor proteins (TSC1, TSC2)
2009/09/24	Calmodulin-Dependent Alteration of Intracellular Localization of Tumor Suppressor Proteins (TSC1, TSC2) (International Tuberous Sclerosis Complex (TSC) Conference: From DNA to Human Therapies)
2009/09/24	Phosphorylation of TSC1 at Residue T417 Results in Mitochondrial Localization and HSP70-Dependent Regulation of Apoptosis (International Tuberous Sclerosis Complex (TSC) Conference: From DNA to Human Therapies)
2007/10/30	Analysis of Gene Expression Related to the One Carbon Metabolic Pathway and DNA Methylation Status in the Rat Livers During Vitamin B-12-Deficiency. (21st International Mammalian Genome Conference　（第21回IMGC2007　国際哺乳類ゲノム会議）)
2007/09/24	Calmodulin (CaM) dependent dissociation of tuberin from membrane. (TUBEROUS SCLEROSIS COMPLEX : FROM GENES TO NEW THERAPEUTICS)
2007/09/24	Direct Interaction of TSC1 gene product hamartin to Hsp70 (TUBEROUS SCLEROSIS COMPLEX：FROM GENES TO NEW THERAPEUTICS)
2007/09/24	Tuberin regulates Rac1 activity and ROS production (TUBEROUS SCLEROSIS COMPLEX：FROM GENES TO NEW THERAPEUTICS)
2006/07/07	Analysis of Huntington's disease transgenic mice based on "Quinolinate hypothesis" (The 11th International Meeting of International Study Group for Tryptophan research (ISTRY-2006))
2006/06/20	Analysis of the relationship between THP excretion and sodium ion reabsorption in rat kidney (20th IUBMB International Congress of Biochemistry and Molecular Biology and 11th FAOBMB Congress)