教員教育・研究情報 - 少作　隆子

ショウサク　タカコ
少作　隆子

所属北陸大学医療保健学部理学療法学科

北陸大学大学院医療保健学研究科（2025年4月1日開設）医療保健学専攻

職種教授

著書・論文歴
著書	Excitatory-Inhibitory Balance: Synapses, Circuits, Systems,99-109頁 (共著) 2003
著書	Slow Synaptic Responses and Modulation,436-437頁 (共著) 2000
著書	イオンチャネル・1,34-43頁 (共著) 1993/05
著書	Electroporation and Electrofusion in Cell Biology,193-202頁 (共著) 1989
著書	新生理科学体系　第３巻,36-43頁 (共著) 1987/03
論文	Action sequence learning is impaired in genetically modified mice with the suppressed GABAergic transmission from the thalamic reticular nucleus to the thalamus. Neuroscience 532,87-102頁 (共著) 2023/11/10
論文	Evaluation of motor learning in predictable loading task using a force sense presentation device Exp Brain Res 240 (12),3305-3314頁 (共著) 2022/12
論文	Effects of environmental enrichment on exploratory behavior, win-stay and lose-shift performance, motor sequence learning, and reversal learning during the three-lever operant task in mice Behav Brain Res 429,113904 (共著) 2022/07/05
論文	Effects of long-term treatment with dietary theobromine on rat skeletal muscles Mol Biol Rep 49 (5),3965-3973頁 (共著) 2022/05
論文	Endocannabinoid Signaling from 2-Arachidonoylglycerol to CB1 Cannabinoid Receptor Facilitates Reward-based Learning of Motor Sequence Neuroscience 421,1-16頁 (共著) 2019/11/21
論文	Corticosterone inhibits the expression of cannabinoid receptor-1 and cannabinoid receptor agonist-induced decrease in cell viability in glioblastoma cells Oncol Lett 18 (2),1557-1563頁 (共著) 2019/08
論文	Hypoxia-induced inhibition of the endocannabinoid system in glioblastoma cells Oncol Rep 38 (6),3702-3708頁 (共著) 2017/12
論文	Theobromine up-regulates cerebral brain-derived neurotrophic factor and facilitates motor learning in mice J Nutr Biochem 39,110-116頁 (共著) 2017/01
論文	Relationship between prediction-based motor control during loading task and motor learning during lever-pressing task J Wellness Health Care 41,37-48頁 (共著) 2017
論文	Electrophysiological evidence showing muscarinic agonist-antagonist activities of N-desmethylclozapine using hippocampal excitatory and inhibitory neurons Brain Res 1642,255-262頁 (共著) 2016/07/01
論文	Probabilistic Selection Taskと予測に基づく運動制御課題の関連金沢大学つるま保健学会誌 40,97-101頁 (共著) 2016
論文	Probabilistic Selection Taskの日本人への応用およびその信頼性の検討作業療法 35,289-300頁 (共著) 2016
論文	フィードフォワードの運動制御課題における加速度波形と筋電図の関連性日本作業療法研究学会雑誌 19 (1),31-35頁 (共著) 2016
論文	若年成人におけるProbabilistic Selection Task成績の性差の検討日本作業療法研究学会雑誌 19 (1),7-14頁 (共著) 2016
論文	Weeding out bad waves: towards selective cannabinoid circuit control in epilepsy Nat Rev Neurosci 16 (5),264-277頁 (共著) 2015/05
論文	Availability of three-lever operant task as mouse model for studying motor sequence and skill learning. Tsuruma Health Sci Soc 39,113-123頁 (共著) 2015
論文	Endocannabinoid-mediated retrograde modulation of synaptic transmission Curr Opin Neurobiol 29,1-8頁 (共著) 2014/12
論文	Impaired anticipatory hand movement during a loading task in patients with schizophrenia. 38,21-28頁 (共著) 2014
論文	Acute inhibition of diacylglycerol lipase blocks endocannabinoid-mediated retrograde signalling: evidence for on-demand biosynthesis of 2-arachidonoylglycerol J Physiol 591 (19),4765-4776頁 (共著) 2013/10/01
論文	Intracellular calcium level is an important factor influencing ion channel modulations by PLC-coupled metabotropic receptors in hippocampal neurons Brain Res 1512,9-21頁 (共著) 2013/05/28
論文	健常者および統合失調症、双極性障害患者における上肢への重りの負荷/脱負荷時の反応と予測の影響日本作業療法研究学会雑誌 16,37-40頁 (共著) 2013
論文	Cannabinoids inhibit peptidoglycan-induced phosphorylation of NF-κB and cell growth in U87MG human malignant glioma cells Oncol Rep 28 (4),1176-1180頁 (共著) 2012/10
論文	Endocannabinoids and retrograde modulation of synaptic transmission Neuroscientist 18 (2),119-132頁 (共著) 2012/04
論文	Cellular heat acclimation regulates cell growth, cell morphology, mitogen-activated protein kinase activation, and expression of aquaporins in mouse fibroblast cells Cell Physiol Biochem 30 (2),450-457頁 (共著) 2012
論文	Effects of clozapine and N-desmethylclozapine on synaptic transmission at hippocampal inhibitory and excitatory synapses Brain Res 1421,66-77頁 (共著) 2011/11/03
論文	Activation of tumor suppressor protein PTEN and induction of apoptosis are involved in cAMP-mediated inhibition of cell number in B92 glial cells Neurosci Lett 497 (1),55-59頁 (共著) 2011/06/15
論文	Neuronal protease-activated receptor 1 drives synaptic retrograde signaling mediated by the endocannabinoid 2-arachidonoylglycerol J Neurosci 31 (8),3104-3109頁 (共著) 2011/02/23
論文	Endocannabinoid-mediated control of synaptic transmission Physiol Rev 89 (1),309-380頁 (共著) 2009/01
論文	Pharmacological evidence for the involvement of diacylglycerol lipase in depolarization-induced endocanabinoid release Neuropharmacology 54 (1),58-67頁 (共著) 2008/01
論文	Endocannabinoid signalling triggered by NMDA receptor-mediated calcium entry into rat hippocampal neurons J Physiol 584,407-418頁 (共著) 2007/10/15
論文	Roles of phospholipase Cbeta and NMDA receptor in activity-dependent endocannabinoid release J Physiol 584,373-380頁 (共著) 2007/10/15
論文	Ca(2+)-assisted receptor-driven endocannabinoid release: mechanisms that associate presynaptic and postsynaptic activities Curr Opin Neurobiol 17 (3),360-365頁 (共著) 2007/06
論文	Endocannabinoids and synaptic function in the CNS. Neuroscientist. 13 (2),127-137頁 (共著) 2007/04
論文	Presynaptic monoacylglycerol lipase activity determines basal endocannabinoid tone and terminates retrograde endocannabinoid signaling in the hippocampus J Neurosci 27 (5),1211-1219頁 (共著) 2007/01/31
論文	The CB1 cannabinoid receptor is the major cannabinoid receptor at excitatory presynaptic sites in the hippocampus and cerebellum J Neurosci. 26 (11),2991-3001頁 (共著) 2006/03/15
論文	Synaptically driven endocannabinoid release requires Ca2+-assisted metabotropic glutamate receptor subtype 1 to phospholipase Cbeta4 signaling cascade in the cerebellum J Neurosci 25 (29),6826-6835頁 (共著) 2005/07/20
論文	Phospholipase Cbeta serves as a coincidence detector through its Ca2+ dependency for triggering retrograde endocannabinoid signal Neuron 45 (2),257-268頁 (共著) 2005/01/20
論文	Calcium signaling and synaptic modulation: regulation of endocannabinoid-mediated synaptic modulation by calcium Cell Calcium 38,369-374頁 (共著) 2005
論文	A novel action of stargazin as an enhancer of AMPA receptor activity Neurosci Res 50 (4),369-374頁 (共著) 2004/12
論文	Two distinct classes of muscarinic action on hippocampal inhibitory synapses: M2-mediated direct suppression and M1/M3-mediated indirect suppression through endocannabinoid signalling Eur J Neurosci 19 (10),2682-2692頁 (共著) 2004/05
論文	Retrograde modulation of synaptic transmission mediated by endogenous cannabinoids. Curr Neuropharmacol 2,49-57頁 (共著) 2004
論文	Postsynaptic M1 and M3 receptors are responsible for the muscarinic enhancement of retrograde endocannabinoid signalling in the hippocampus Eur J Neurosci 18 (1),109-116頁 (共著) 2003/07
論文	Presynaptic cannabinoid sensitivity is a major determinant of depolarization-induced retrograde suppression at hippocampal synapses J Neurosci 22 (10),3864-3872頁 (共著) 2002/05/15
論文	Cooperative endocannabinoid production by neuronal depolarization and group I metabotropic glutamate receptor activation Eur J Neurosci 15 (6),953-961頁 (共著) 2002/03
論文	Retrograde signaling at central synapses via endogenous cannabinoids Mol Psychiatry 7 (3),234-235頁 (共著) 2002/03
論文	Endogenous cannabinoid as a retrograde messenger from depolarized postsynaptic neurons to presynaptic terminals Neurosci Res 40 (3),205-210頁 (共著) 2001/07
論文	Endogenous cannabinoids mediate retrograde signals from depolarized postsynaptic neurons to presynaptic terminals Neuron 29 (3),729-738頁 (共著) 2001/03
論文	Heterosynaptic expression of depolarization-induced suppression of inhibition (DSI) in rat hippocampal cultures Neurosci Res 36 (1),67-71頁 (共著) 2000/01
論文	Distribution and properties of kainate receptors distinct in the CA3 region of the hippocampus of the guinea pig Brain Res 783 (2),227-235頁 (共著) 1998/02/09
論文	Properties of depolarization-induced suppression of inhibitory transmission in cultured rat hippocampal neurons Pflugers Arch. 435 (2),273-279頁 (共著) 1998/01
論文	Presence of the voltage-gated potassium channels sensitive to charybdotoxin in inhibitory presynaptic terminals of cultured rat hippocampal neurons Neurosci Lett 207 (3),195-198頁 (共著) 1996/04/05
論文	Effects of metabotropic glutamate receptor agonists on excitatory and inhibitory transmissions in cultured rat hippocampal neurons Brain Res. 705,337-340頁 (共著) 1995/12/24
論文	Baclofen inhibits GABAergic transmission after treatment with type-specific calcium channel blockers in cultured rat hippocampal neurons Neurosci Lett 187 (3),205-208頁 (共著) 1995/03/10
論文	Contributions of multiple calcium channel types to GABAergic transmission in rat cultured hippocampal neurons Neurosci Lett 181,145-148頁 (共著) 1994/11/07
論文	Augmenting action of nicotine on population spikes in the dentate gyrus of the guinea pig Neurosci Res. 20 (4),317-322頁 (共著) 1994/10
論文	Long-term potentiation and depression in the dentate gyrus, and effects of nicotine Neurosci Res 20 (4),323-329頁 (共著) 1994/10
論文	A comparison between potencies of external calcium, strontium and barium to support GABAergic synaptic transmission in rat cultured hippocampal neurons Neurosci Res 20 (3),223-229頁 (共著) 1994/09
論文	Electrostatic cell-to-cell adhesion by a non-proteolytic component in a protease preparation Cell Struct Funct 19 (3),165-172頁 (共著) 1994/06
論文	Suppression of hippocampal synaptic transmission by the spider toxin omega-agatoxin-IV-A Brain Res 634 (2),349-352頁 (共著) 1994/01/21
論文	Single-channel recordings of an ATP-sensitive K channel in rat cultured cortical neurons. Ann N Y Acad Sci. 707,396-398頁 (共著) 1993/12/20
論文	ATP-sensitive K+ channel activators suppress the GABAergic inhibitory transmission by acting on both presynaptic and postsynaptic sites in rat cultured hippocampal neurons. Neurosci Lett. 159,139-142頁 (共著) 1993/09/03
論文	Electrophysiological features of habenular neurons of the guinea pig: high efficacy of synaptic transmission and variable configuration of unitary spikes. Neurosci Lett. 154,179-182頁 (共著) 1993/05/14
論文	Quantal analysis of modulating action of adenosine on the mossy fiber synapse in hippocampal slices. Hippocampus. 3 (1),87-92頁 (共著) 1993/01
論文	Identification of an ATP-sensitive K+ channel in rat cultured cortical neurons. Pflugers Arch. 422 (3),260-266頁 (共著) 1992/12
論文	Regulation of inwardly rectifying K+ channels by intracellular pH in opossum kidney cells. Pflugers Arch. 416,138-143頁 (共著) 1990/04
論文	Relationship between cytosolic activities of calcium and pH in frog proximal tubules. Jpn J Physiol. 40,273-296頁 (共著) 1990
論文	Electric Currents Associated With Directed Migration of Fibroblasts. Biol Bull. 176,123-125頁 (共著) 1989/04
論文	Reciprocal effects of Ca2+ and Mg-ATP on the 'run-down' of the K+ channels in opossum kidney cells. Pflugers Arch. 413 (5),562-564頁 (共著) 1989/03
論文	Chloride effect on a neutral-carrier-based pH-sensitive microelectrode and its intracellular application. Bull Osaka Med Coll. 34,13-26頁 (共著) 1988/11
論文	Cytosolic ADP enhances the sensitivity to tolbutamide of ATP-dependent K+ channels from pancreatic B-cells. FEBS Lett. 239 (2),241-244頁 (共著) 1988/11
論文	Forskolin-induced block of delayed rectifying K+ channels in pancreatic beta-cells is not mediated by cAMP. Pflugers Arch. 411 (6),613-619頁 (共著) 1988/06
論文	Evidence for the involvement of calmodulin in the operation of Ca-activated K channels in mouse fibroblasts. J Membr Biol. 96 (2),121-128頁 (共著) 1987/06
論文	Dual effects of ATP on K+ currents of mouse pancreatic beta-cells. Pflugers Arch. 408 (2),133-138頁 (共著) 1987/02
論文	Opposite effects of tolbutamide and diazoxide on the ATP-dependent K+ channel in mouse pancreatic beta-cells. Pflugers Arch. 407 (5),493-499頁 (共著) 1986/11
論文	Intracellular Ca2+ and calmodulin regulate the K+ conductance in cultured fibroblasts. Biomed Res 7 (Suppl),73-78頁 (共著) 1986
論文	Electric pulse-induced fusion of mouse lymphoma cells: roles of divalent cations and membrane lipid domains. J Membr Biol. 85 (3),269-280頁 (共著) 1985/10
論文	Ca2+ is prerequisite for cell fusion induced by electric pulses Biomed Res 5,511-515頁 (共著) 1984/12
論文	Exogenous ATP induces electrical membrane responses in fibroblasts. Exp Cell Res. 152 (2),552-557頁 (共著) 1984/06
論文	Somatic hybridization between human and mouse lymphoblast cells produced by an electric pulse-induced fusion technique. Cell Struct Funct. (共著) 1984/06
論文	Facilitation of electrofusion of mouse lymphoma cells by the proteolytic action of proteases. Biochem Biophys Res Commun. 120 (1),138-143頁 (共著) 1984/04/16
論文	Concentration of mast-cell progenitors in bone marrow, spleen, and blood of mice determined by limiting dilution analysis. J Cell Physiol. 112 (1),136-140頁 (共著) 1982/07
論文	Spleen colony-forming cell as common precursor for tissue mast cells and granulocytes. Nature 291 (5811),159-160頁 (共著) 1981/05/14
その他	前頭葉・実行機能プログラム〈FEP〉～認知機能改善のためのトレーニング実践マニュアル・臨床家ガイド付き～ (共著) 2015
その他	イラストレイテッド生理学,18-30頁 (共著) 2014/12
その他	【生命を支える脂質-最新の研究と臨床】脂質メディエーターと受容体・産生酵素　2-アラキドノイルグリセロールの逆行性シグナルとしての役割医学のあゆみ 248 (13),1009-1013頁 (単著) 2014
その他	脳内マリファナ物質の働きおよびその生成・消去メカニズム金沢大学十全医学会雑誌 116 (2),68-69頁 (単著) 2007
その他	脳内マリファナ類似物質発生のメカニズム生化学 78 (2),126-130頁 (共著) 2006/02
その他	【記憶・学習の分子基盤に迫る】　マリファナ類似物質の逆行性伝達物質としての役割 Molecular Medicine 41 (9),1087-1094頁 (共著) 2004
その他	Basic Neuroscience　カンナビノイド受容体 Annual Review神経　2003 2003,18-24頁 (共著) 2003
その他	【イオンチャネルの最前線】　臓器でのイオンチャネルの働きと疾患　グルタミン酸受容体チャネルとシナプス可塑性医学のあゆみ 201 (13),1123-1127頁 (共著) 2002
その他	カンナビノイド受容体と逆行性シグナル伝達 Clinical Neuroscience 19 (12),1431-1432頁 (共著) 2001
その他	ニューロサイエンスの話題　脳内カンナビノイド受容体とシナプス伝達調節脳の科学 23 (11),1000-1002頁 (共著) 2001
その他	生理学実習法　ポリエチレンチューブによる心筋細胞活動電位の記録日本生理学雑誌 63 (4),87-91頁 (共著) 2001
その他	【チャンネル病】イオンチャンネル,イオンポンプ,トランスポーターの基礎　生理学的機能解析法及び分子生物学的解析法脳の科学 21 (増刊),21-26頁 (単著) 1999
その他	Ion-selective microelectrodes to study proton and bicarbonate transport in the renal epithelium. Kidney Int Suppl. 33,S23-S28頁 (共著) 1991/07
その他	Regulation of K+ channels in proximal tubules: Studies in opossum kidney cells. Nephrology 第2巻,1677-1684頁 (共著) 1991
その他	電気的刺激による細胞融合法生体の科学 35,378-383頁 (共著) 1984