教員教育・研究情報 - 光本　泰秀

ミツモト　ヤスヒデ Yasuhide Mitsumoto
光本　泰秀

所属北陸大学薬学部薬学科

職種教授

著書・論文歴
その他	未病対策にアプローチできる薬剤師に求められるもの－統合医療を支える補完代替療法－日本未病学会誌 31 (1),25-29頁 (単著) 2025/04
著書	補完代替医療特論-薬学教育における補完代替医療- 応用細胞補完代替医療学第2巻,15-23頁 (単著) 2022/12
論文	Rapid eye movement sleep deprivation enhances vulnerability of striatal dopaminergic neurons to 1‐methyl‐4‐phenyl‐1,2,3,6‐tetrahydropyridine neurotoxicity in mice. Psychogeriatrics 20,129-130頁 (共著) 2020/01
論文	Psychosocial stress enhances susceptibility to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine neurotoxicity in C57BL/6N mice. Biomed Res 40 (6),251-255頁 (共著) 2019/12
論文	Rubiscolin-6, a δ-Opioid Peptide from Spinach Rubisco, Exerts Antidepressant-Like Effect in Restraint-Stressed Mice. Journal of Nutritional Science and Vitaminology 65 (2),202-204頁 (共著) 2019/04
論文	Acute restraint stress augments 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine neurotoxicity via increased toxin uptake into the brain in C57BL/6 mice. Neuroscience Bulletin 34 (5),849-853頁 (共著) 2018/10
論文	Genetic influence of dopamine receptor, dopamine transporter, and nicotine metabolism on smoking cessation and nicotine dependence in a Japanese population. BMC Genet. 15 (1),151 (共著) 2014/12
論文	Attenuation of nicotine-evoked Ca2+ influx by antibody to the nicotinic acetylcholine receptor α3 subunits in human embryonic kidney cells Advances in Bioscience and Biotechnology 4 (6A),9-14 (共著) 2013/06
論文	Autoantibody-induced internalization of nicotinic acetylcholine receptor α3 subunit exogenously expressed in human embryonic kidney cells. J Neuroimmunol. 257 (1-2),102-6 (共著) 2013/04
論文	Association between dopamine receptor 2 TaqIA polymorphisms and smoking behavior with an influence of ethnicity: a systematic review and meta-analysis update. Nicotine Tob Res. 15 (3),633-42 (共著) 2013/03
論文	Effects of moderating factors including serotonin transporter polymorphisms on smoking behavior: a systematic review and meta-analysis update. Nicotine Tob Res. 15 (2),572-82 (共著) 2013/02
著書	補完代替医療の現状‐特に中枢神経疾患に関して‐ 応用細胞補完代替医療学第1巻,12-18頁 (単著) 2012/12
論文	Magnolol Protects against MPTP/MPP(+)-Induced Toxicity via Inhibition of Oxidative Stress in In Vivo and In Vitro Models of Parkinson's Disease. Parkinsons Dis. 2012 (985157),9 pages (共著) 2012/05
論文	Oral administration of coenzyme Q(10) reduces MPTP-induced loss of dopaminergic nerve terminals in the striatum in mice. Neurological Sciences 33 (1),195-9 (共著) 2012/02
論文	Loss of striatal dopaminergic terminals during the early stage in response to MPTP injection in C57BL/6 mice Neuroscience Research 69 (4),352-355 (共著) 2011/04
論文	Oral administration of coenzyme Q10 prevents cytochrome c release from mitochondria induced by 1-methyl-4-phenylpyridinium ion in mouse brain synaptosomes Neuroscience Letters 463 (1),22-25 (共著) 2009/09
論文	Atypical antipsychotics suppress production of proinflammatory cytokines and up-regulate interleukin-10 in lipopolysaccharide-treated mice Progress in Neuro-Psychopharmacology and Biological Psychiatry 33 (2),303-307 (共著) 2009/03
論文	Enhanced susceptibility to MPTP neurotoxicity in magnesium-deficient C57BL/6N mice Neuroscience Research 63 (1),72-75 (共著) 2009/01
論文	Mitochondrial Nutrition as a Strategy for Neuroprotection in Parkinson's Disease-Research Focus in the Department of Alternative Medicine and Experimental Therapeutics at Hokuriku University Evidence-Based Complementary and Alternative Medicine (eCAM) 4 (2),263-265 (単著) 2007/06
論文	Age-related severity of dopaminergic neurodegeneration to MPTP neurotoxicity causes motor dysfunction in C57BL/6 mice Neurosci Lett. 40 (1-2),183-187頁 (共著) 2006/06
論文	1H MRS identifies lactate rise in the striatum of MPTP-treated C57BL/6 mice Eur J Neurosci. 23 (4),1077-1081頁 (共著) 2006/02
論文	Honokiol-induced neurite outgrowth promotion depends on activation of extracellular signal-regulated kinases (ERK1/2) Eur J Pharmacol. 516 (2),112-117頁 (共著) 2005/06
論文	Neural mechanisms underlying motor dysfunction as detected by the tail suspension test in MPTP-treated C57BL/6 mice Neurosci Res. 51 (3),265-274頁 (共著) 2005/03
論文	Neuroprotective effects of 2,5-diaryl-3,4-dimethyltetrahydrofuran neolignans Biol Pharm Bull 28 (2),289-293頁 (共著) 2005/02
論文	Differential effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in the olfactory bulb and the striatum in mice 51 (1),111-115頁 (共著) 2005/01
論文	Olfactory impairment and Parkinson's disease-like symptoms observed in the common marmoset following administration of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine Acta Otolaryngol Suppl (533),80-84頁 (共著) 2004/08
論文	Neurotrophic effects of talaumidin, a neolignan from Aristolochia arcuata, in primary cultured rat cortical neurons Planta Med 70,598-602頁 (共著) 2004/07
論文	Efficient synthesis and structure-activity relationship of honokiol, a neurotrophic biphenyl-type neolignan Bioorg Med Chem Lett 17,2621-2625頁 (共著) 2004/05
論文	Honokiol and magnolol induce Ca2+ mobilization in rat cortical neurons and human neuroblastoma SH-SY5Y cells Eur J Pharmacol 474,199-204頁 (共著) 2003/08
論文	1-methyl-4-phenylpyridinium (MPP+) decreases mitochondrial oxidation-reduction (REDOX) activity and membrane potential (Deltapsi(m)) in rat Exp Neurol 179,103-110頁 (共著) 2003/01
論文	Alteration of methamphetamine-induced striatal dopamine release in mint-1 knockout mice Neurosci Res 43,251-257頁 (共著) 2003/07
論文	Intracerebral adenosine infusion improves neurological outcome after transient focal ischemia in rats Neurol Res 24,317-323頁 (共著) 2002/04
論文	Neurotrophic activity of honokiol on the cultures of fetal rat cortical neurons Bioorg Med Chem Lett 12,1163-1166頁 (共著) 2002/04
論文	Stimulation of the regrowth of MPP+-damaged dopaminergic fibers by the treatment of mesencephalic cultures with basigin J Neural Transm (Vienna) 108,1127-1134頁 (共著) 2001/10
論文	Identification and characterization of TMEFF2, a novel survival factor for hippocampal and mesencephalic neurons Genomics 67,146-152頁 (共著) 2000/07
論文	Adenovirus-mediated gene transfer of glial cell line-derived neurotrophic factor prevents ischemic brain injury after transient middle cerebral artery occlusion in rats J Cereb Blood Flow Metab 19,1336-1344頁 (共著) 1999/12
論文	Immunoreactive Akt, PI3-K and ERK protein kinase expression in ischemic rat brain Neurosci Lett 274,45-48頁 (共著) 1999/10
論文	Induction of glial cell line-derived neurotrophic factor receptor proteins in cerebral cortex and striatum after permanent middle cerebral artery occlusion in rats Brain Res 834,190-195頁 (共著) 1999/07
論文	Induction of DNA fragmentation and HSP72 immunoreactivity by adenovirus-mediated gene transfer in normal gerbil hippocampus and ventricle J Neurosci Res 54,38-45頁 (共著) 1998/10
論文	DNA fragmentation and HSP72 gene expression by adenovirus-mediated gene transfer in postischemic gerbil hippocampus and ventricle Metab Brain Dis 13,211-223頁 (共著) 1998/09
論文	Spontaneous regeneration of nigrostriatal dopaminergic neurons in MPTP-treated C57BL/6 mice Biochem Biophys Res Commun 248,660-663頁 (共著) 1998/07
論文	Reduction of ischemic brain injury by topical application of glial cell line-derived neurotrophic factor after permanent middle cerebral artery occlusion in rats Stroke 29,1417-1422頁 (共著) 1998/07
論文	Ameliorative effect of glial cell line-derived neurotrophic factor on brain edema formation after permanent middle cerebral artery occlusion in rats Neurol Res 20,333-336頁 (共著) 1998/06
論文	Defect of an early event of glucose metabolism in skeletal muscle of the male Otsuka Long-Evans Tokushima Fatty (OLETF) rat, a non-insulin-dependent diabetes mellitus (NIDDM) model Biochem Biophys Res Commun 245,378-381頁 (共著) 1998/04
論文	The insulin-dependent biosynthesis of GLUT1 and GLUT3 glucose transporters in L6 muscle cells is mediated by distinct pathways. Roles of p21ras and pp70 S6 kinase J Biol Chem 270,24678-24681頁 (共著) 1995/10
論文	Regulation of cell surface GLUT1, GLUT3, and GLUT4 by insulin and IGF-I in L6 myotubes FEBS Lett 368,19-22頁 (共著) 1995/07
論文	Expression of vesicle-associated membrane protein 2 (VAMP-2)/synaptobrevin II and cellubrevin in rat skeletal muscle and in a muscle cell line Biochem J 304,139-145頁 (共著) 1994/11
論文	Subcellular distribution and immunocytochemical localization of Na,K-ATPase subunit isoforms in human skeletal muscle Mol Membr Biol 11,255-262頁 (共著) 1994/10
論文	A long-lasting vitamin C derivative, ascorbic acid 2-phosphate, increases myogenin gene expression and promotes differentiation in L6 muscle cells Biochem Biophys Res Commun 199,394-402頁 (共著) 1994/02
論文	Regulation of glucose and ion transporter expression during controlled differentiation and fusion in rat skeletal muscle cells. Endocrine J 1,307-315頁 (共著) 1993/10
論文	What signals are involved in the stimulation of glucose transport by insulin in muscle cells? Cell Signal 5,519-529頁 (共著) 1993/09
論文	Hormonal regulation of glucose transporters in muscle cells in culture J Endocrinol Invest 16,147-162頁 (共著) 1993/02
論文	Biochemical and immunocytochemical localization of the 'GLUT5 glucose transporter' in human skeletal muscle Biochem J 286,339-343頁 (共著) 1992/09
論文	Characterization of D-aspartic acid uptake by rat hippocampal slices and effect of ischemic conditions J Neurochem 59,616-621頁 (共著) 1992/08
論文	Detection of the GLUT3 facilitative glucose transporter in rat L6 muscle cells: regulation by cellular differentiation, insulin and insulin-like growth factor-I Biochem Biophys Res Commun 186,1129-1137頁 (共著) 1992/07
論文	Stimulation of glucose transport in L6 muscle cells by long-term intermittent stretch-relaxation FEBS Lett 30,94-98頁 (共著) 1992/04
論文	Insulin induces translocation of the alpha 2 and beta 1 subunits of the Na+/K(+)-ATPase from intracellular compartments to the plasma membrane in mammalian skeletal muscle J Biol Chem 267,5040-5043頁 (共著) 1992/03
論文	Development regulation of the subcellular distribution and glycosylation of GLUT1 and GLUT4 glucose transporters during myogenesis of L6 muscle cells J Biol Chem 267,4957-4962頁 (共著) 1992/03
論文	Acute and long-term effects of insulin-like growth factor I on glucose transporters in muscle cells. Translocation and biosynthesis FEBS Lett 298,285-290頁 (共著) 1992/02
論文	Characterization of the uptake of adenosine by cultured rat hippocampal cells and inhibition of the uptake by xanthine derivatives Neurosci Lett 133,275-278頁 (共著) 1991/12
論文	Differential expression of the GLUT1 and GLUT4 glucose transporters during differentiation of L6 muscle cells Biochem Biophys Res Commun 175,652-659頁 (共著) 1991/03
論文	Reconstitution of the L-leucine-H+ cotransporter of the plasma membrane from Chang liver cells into proteoliposomes Biochim Biophys Acta 1061,171-174頁 (共著) 1991/01
論文	Dual-fluorescence flow cytometric analysis of membrane potential and cytoplasmic free Ca2+ concentration in embryonic rat hippocampal cells Cell Struct Funct 14,669-672頁 (共著) 1989/12
論文	Functional expression of a subtype of the Ca2+ channels in the embryonic rat hippocampus as detected by dual-fluorescence flow cytometric analysis Neurosci Lett 106,141-146頁 (共著) 1989/11
論文	Possible participation of calmodulin in stimulation of leucine transport by concanavalin A in human lymphocytes Biochem Biophys Res Commun 153,570-575頁 (共著) 1988/06
論文	Leucine transport-induced activation of the Na+/H+ exchanger in human peripheral lymphocytes Biochim Biophys Acta 939,349-354頁 (共著) 1988/04
論文	Stimulation of leucine transport by a mitogen through intracellular Ca2+ increase in human peripheral lymphocytes Biochim Biophys Acta 968,353-358頁 (共著) 1988/03
論文	Stimulation of leucine transport by a phorbol ester through activation of protein kinase C and Na+/H+ exchanger Biochem Biophys Res Commun 144,900-906頁 (共著) 1987/04
論文	Leucine transport in relation to the activities of Na+-H+ antiporter and Na+/K+ pump stimulated by serum and a tumor promoter Biochim Biophys Acta 861,187-193頁 (共著) 1986/09
論文	Leucine-proton cotransport system in Chang liver cell J Biol Chem 261,4549-4954頁 (共著) 1986/04
論文	Leucine transport coupled to proton movement in membrane vesicles from Chang liver cells Biochem Int 7,159-167頁 (共著) 1983/04